Innovative Depression Treatments That Saved My Life

Innovative Depression Treatments That Saved My Life

Matt Rodriguez • September 2, 2025

Depression is one of the most common mental health conditions, affecting millions of people across all walks of life. While many find relief through traditional methods, they don’t work for everyone. Some people can struggle with depression for nearly a lifetime, and in severe cases, may even consider taking their own lives. 

At The Albany Clinic, we specialize in innovative, evidence-based treatments that can help patients overcome depression, even when other therapies haven’t worked. In this article, we’ll discuss these treatments and how clinics such as our own are saving lives. 


When Traditional Therapies Aren’t Enough

For some people living with depression, the usual treatments–therapy, SSRIs, lifestyle changes—just don’t go far enough. Roughly 30% of people with major depressive disorder (MDD) experience treatment-resistant depression (TRD)

TRD means that even after trying multiple recognized treatments, the symptoms don’t ease up. This emotional weight can become unbearable, as they feel like they’ve exhausted every option with no hope.

At its worst, TRD isn’t just a mental condition; it’s life-threatening. People can feel demoralized and may see suicide as the only way out. Studies show nearly one-third of those with TRD attempt suicide at some point. That’s why we provide innovative treatments at the Albany Clinic, helping prevent people from reaching this point.

IV Ketamine at The Albany Clinic 

One of our treatments includes intravenous (IV) ketamine therapy. Unlike standard therapies, which can take weeks to have an effect, ketamine can significantly reduce symptoms of depression within hours, as well as thoughts of suicide. This quick action is particularly valuable for individuals in acute mental health crises, providing a crucial window for stabilization and recovery.

In one clinical trial, 55% of individuals with treatment-resistant depression experienced at least a 50% reduction in symptoms after just three weeks of twice-weekly IV ketamine treatments. In another study, suicidal thoughts were resolved within just 230 minutes

Ketamine is used “off-label” to treat TRD and other types of depression, including bipolar depression and postpartum depression. It can also treat other mental health conditions, making it especially helpful for individuals with co-occurring disorders, such as depression with anxiety or obsessive-compulsive disorder (OCD). 

How Ketamine Changed Tammi’s Life

Tammi Pinski is one of the many patients who have regained quality of life after undergoing ketamine therapy at our clinic. Tammi left this review on Google:


When I thought there were no other options, The Albany clinic was my last hope. Chronic Depression, PTSD, and an Anxiety Disorder had returned after a several year reprieve.

I had been on medications, supported by other medication’s and was feeling defeated. I remember hearing a local physician mention the new “clinic” and with nothing to lose, I made the call.


From the moment I spoke with Sylvia - I knew I was in good hands. After my initial consultation with Dr. Garwin, meeting the nursing staff and receiving an IV infusion,
I experienced IMMEDIATE relief.


Coupled with IV infusion therapy Dr. Garwin gave me expectations to meet outside of the clinic that included working with a medication specialist and a therapist — all have made
an immense difference in my life.


Spravato: An FDA-Approved Medicine for TRD 

The Albany Clinic is a registered provider of Spravato (esketamine) - a nasal spray medication derived from ketamine. This medication is FDA-approved to treat treatment-resistant depression (TRD) and major depression with suicidal thoughts (MSDI). For patients who qualify, this approval often means that insurance can help cover the cost, making the treatment financially accessible.

Like IV ketamine, patients can experience relief from symptoms within hours. In real-world settings, over 60% of Spravato users reported significant relief according to an analysis. This rapid action also provides critical stabilization for those in crisis.

TMS: A Slower But Steady Solution

Transcranial Magnetic Stimulation (TMS) is a non-invasive treatment that uses magnetic pulses to activate areas of the brain linked to mood. It’s also FDA-approved for depression and has shown strong results in people with TRD.

While it works more gradually than Spravato, the outcomes can be powerful. In one clinical study, 63% of patients saw significant improvement after a full course of TMS, and over 40% experienced complete remission, meaning their depression symptoms completely resolved.

What Patients Are Telling Us 

At the Albany Clinic, we offer life-changing care for people living with depression. Our team provides innovative treatments like IV ketamine, Spravato, and TMS to help patients take back control of their well-being. With a compassionate staff and a supportive, calming environment, we ensure safety, comfort, and the best possible outcome from these treatments.

Here’s what our patients have had to say about our services:


“Dr Garwin and his staff helped me when I didn’t think there was anything left to try.
The Albany clinic has changed my life.

  • Hunter Clark


This place is literally working miracles. The doctors are the best in their field and the staff they employ and the environment they’ve created are absolute top tier quality. The best place for healing. They genuinely care about each and every one of their patients with kindness and compassion. Best bedside manner.”

  • Mini Yak


Safe, professional, and individualized experience. Doctor and staff are very knowledgeable and responsive to your questions and concerns; making treatment experience exceptional. Highly recommend for those who have searched for options.”

  • Clautus Bierman



If you need healing and want to see how the Albany Clinic can help you, be sure to
get in touch today.

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By Kimberly Mercille September 4, 2025
Living with post-traumatic stress disorder (PTSD) can be debilitating. Nightmares, flashbacks, and a constant sense of being “on edge” can interfere with work, relationships, and overall quality of life. If you’ve tried therapy or medications without lasting relief, you’re not alone—and there may be another option. At the Albany Clinic in Carbondale, Illinois, we specialize in ketamine therapy as a promising treatment for PTSD. Understanding PTSD Post-traumatic stress disorder (PTSD) develops after experiencing or witnessing trauma. While everyone responds to trauma differently, common symptoms include: Intrusive memories or flashbacks Avoidance of reminders of the trauma Emotional numbness or detachment Heightened anxiety , irritability , or trouble sleeping Some people also develop complex PTSD (CPTSD) , which stems from repeated or prolonged trauma. CPTSD often comes with additional challenges, such as difficulty regulating emotions or maintaining healthy relationships. Current Treatments and Their Limitations The most common treatments for PTSD include cognitive behavioral therapy (CBT) , eye movement desensitization and reprocessing (EMDR) , and antidepressant medications . For many people, these treatments can be helpful. However, they also come with challenges: Medications may take weeks to work and don’t help everyone. Therapy can take months or years to create lasting change. Therapies can be difficult to engage with, as they involve discussing the trauma, which can be distressing or may cause someone to shut down emotionally. Some individuals continue to experience severe symptoms despite treatment. This is where ketamine therapy offers a new avenue of hope. How Ketamine May Help PTSD Ketamine works differently from traditional antidepressants. Instead of gradually altering brain chemistry, ketamine acts quickly on key brain circuits involved in mood and fear. Rebalancing brain activity : Ketamine boosts activity in the prefrontal cortex , the part of the brain that helps regulate emotions. It also decreases activity in the amygdala , the brain’s fear center, helping reduce anxiety and hypervigilance. Promoting neuroplasticity : Ketamine encourages new connections between brain areas, helping “rewire” pathways associated with PTSD symptoms. Supporting fear extinction : Ketamine supports fear extinction, the process by which the brain ‘unlearns’ fearful responses to things it expects to be threatening. This is especially important in PTSD, where people may react to safe situations or cues as if they were actual threats. Benefits of Ketamine for PTSD Research continues to grow, but studies and clinical experience have shown several promising benefits: Rapid relief : Many patients notice improvements within hours to days, rather than weeks. This can be especially important during a mental health crisis or for those struggling with suicidal thoughts. Effective when other treatments have failed : Ketamine can offer relief even for people who haven’t responded to medications or therapy. Sustained improvement : With a series of treatments, many patients experience lasting relief from PTSD symptoms. Increases the benefits of other therapies : Ketamine may speed up the outcomes of other trauma-based therapies, such as prolonged exposure therapy . In a 2021 study , people with severe PTSD received either ketamine or a comparison drug over two weeks. Those given ketamine showed much faster and greater improvement in PTSD and depression symptoms. About 67% had significantly improved symptoms , with the biggest differences in intrusive memories, avoidance, and negative thoughts and mood. The treatment was also well-tolerated with few adverse effects. Ketamine Treatment for PTSD at the Albany Clinic At the Albany Clinic in Carbondale, Illinois, we are dedicated to providing safe, effective ketamine therapy for people with PTSD and other psychiatric disorders. We administer ketamine intravenously to support a rapid reduction in symptoms. Here’s what you can expect: A thorough medical and psychiatric evaluation before treatment begins Comfortable, private treatment rooms Careful monitoring by experienced medical professionals throughout each session A personalized treatment plan designed around your needs During your treatment, you’ll have a small plastic catheter inserted into a vein in your arm, which will deliver ketamine straight into your bloodstream. You may experience mild side effects, such as dizziness and dissociation , which can make you feel disconnected from your body and the world around you. These typically wear off after the session is finished. The infusion takes 45 minutes to one hour , and you’ll be closely monitored by staff during the infusion and afterwards to ensure your safety. We’ll provide you with guidance on aftercare once you’re done and how to make the most of your new headspace. Most people with PTSD require multiple infusions to experience sustained, meaningful changes. However, the treatment plan will be tailored according to your unique needs. Get in Touch Today If you or a loved one is struggling with PTSD and current treatments haven’t provided the relief you need, ketamine therapy may be an option worth exploring. At the Albany Clinic, we are here to answer your questions and guide you through every step of the process. Get in touch to find out more.
By Kimberly Mercille July 9, 2025
As ketamine therapy becomes increasingly popular for treating mental health conditions like depression and PTSD, more people are exploring their options. At-home ketamine therapy gained traction during the pandemic for its convenience, but without medical supervision, this approach may come with elevated risks. In this article, we’ll explore some of the key differences and pros and cons of in-clinic versus at-home ketamine therapy. What Is In-Clinic Ketamine Therapy? IV Ketamine Treatment In-clinic ketamine therapy involves receiving treatment at a licensed medical facility, such as The Albany Clinic , where professionals monitor and administer the medication under strict protocols. This ensures your safety, especially during your initial sessions. At The Albany Clinic, we specialize in intravenous (IV) ketamine infusion therapy , which has been most well-researched when it comes to treating mental health disorders. IV ketamine bypasses the digestive system, delivering the medication directly into the bloodstream. IV ketamine can help relieve symptoms of various mental health disorders, including depression , anxiety , post-traumatic stress disorder (PTSD) , and more. During an infusion at our clinic, you’ll rest in a calm, controlled environment while ketamine is delivered into a vein through a catheter. Our trained staff will closely monitor your vital signs and mental state throughout the session, adjusting the dose of ketamine if needed. We’ll observe you after treatment to ensure any side effects are managed promptly and effectively. Spravato We also offer Spravato (esketamine) at our clinic, a nasal spray based on ketamine. Unlike other forms of ketamine treatment, Spravato is approved by the FDA and is specifically for adults with treatment-resistant depression or major depressive disorder with suicidal thoughts . Spravato is only approved for in-clinic use under professional supervision and cannot be administered at home, making clinical oversight a legal and medical necessity for this treatment option. During a Spravato session, you’ll self-administer the medication under the supervision of our medical staff. We’ll then closely monitor you for a couple of hours to ensure you’re safe and all side effects have subsided before leaving. What Is At-Home Ketamine Therapy? At-home ketamine therapy allows patients to self-administer the ketamine, typically in the form of lozenges or nasal sprays, delivered via mail. While this option offers flexibility, it usually involves minimal supervision , often limited to virtual check-ins with healthcare providers. Some at-home providers offer optional video support during sessions, but this is not always the case. Patients are largely responsible for monitoring their own physical and emotional reactions, without the benefit of immediate medical intervention if adverse effects occur. At-home treatment often includes supplementary materials , such as guided meditations or journaling tools. However, the lack of real-time clinical oversight makes this option less ideal for those with complex or severe mental health needs. Safety Considerations: In-Clinic vs. At-Home While ketamine therapy is considered safe for most patients, it does come with potential physical and psychological side effects , including: Physical Risks: Elevated blood pressure or heart rate Nausea or vomiting Sedation or dizziness Impaired coordination Rare allergic reactions Psychological Risks: Hallucinations or dissociation Temporary confusion or anxiety Emotional vulnerability during treatment Risk of misuse or dependency The FDA has issued warnings about at-home ketamine use due to its potential for abuse and lack of medical supervision . Without proper monitoring, the risk of addiction and long-term complications, such as bladder damage and cognitive decline, may increase. Key Differences Between In-Clinic and At-Home Ketamine Therapy
By Matt Rodriguez July 8, 2025
Intravenous (IV) ketamine has emerged as a promising option for individuals struggling with treatment-resistant depression and other hard-to-treat mental health conditions. Ketamine was originally developed as an anesthetic, but is now being used in controlled medical settings to deliver rapid relief when traditional therapies fall short. This guide explores the history, science, benefits, and practical considerations of IV ketamine therapy and what you can expect from treatment at The Albany Clinic.